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Recruiting older patients with peripheral arterial disease: evaluating challenges and strategies

Authors Brostow DP, Hirsch AT, Kurzer MS

Received 21 February 2015

Accepted for publication 10 April 2015

Published 6 August 2015 Volume 2015:9 Pages 1121—1128

DOI https://doi.org/10.2147/PPA.S83306

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Editor who approved publication: Dr Johnny Chen

Diana P Brostow,1 Alan T Hirsch,2 Mindy S Kurzer3,4

1Veterans Affairs Eastern Colorado Health Care System, Denver, CO, USA; 2Department of Medicine, Vascular Medicine Program, University of Minnesota, Twin Cities, Minneapolis, MN, USA; 3Department of Food Science and Nutrition, University of Minnesota, Twin Cities, 4Healthy Lives Institute, St Paul, MN, USA

Abstract: Peripheral arterial disease (PAD) is a group of syndromes characterized by chronic and progressive atherosclerosis with a high burden of physical disability and cardiovascular morbidity and mortality. Recruiting patients for clinical research is therefore challenging. In this article, we describe and evaluate our methods for recruiting participants for a cross-sectional feasibility study of PAD, nutritional status, and body composition. We used convenience and purposive sampling approaches to identify potential participants. Between May 2012 and April 2013, 1,446 patients were identified, and 165 patients (11.4%) responded to recruitment requests. The final enrollment was 64 participants (64/1,446; 4.4%), and four subjects (6.3%) subsequently withdrew from the study. Recruiting PAD patients presents a variety of challenges, due largely to the burdens of living with coexistent illnesses, and patients’ reluctance or inability to travel for research. In this article, we delineate suggestions for improving the efficacy of recruitment methods in future PAD studies.

Keywords: community-based programs, depression, ethnicity, geriatrics, progressive illness and disease, mental health and illness, minorities

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