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Recent advances in functional nanostructures as cancer photothermal therapy

Authors Hussein EA, Zagho MM, Nasrallah GK, Elzatahry AA

Received 28 December 2017

Accepted for publication 13 February 2018

Published 17 May 2018 Volume 2018:13 Pages 2897—2906

DOI https://doi.org/10.2147/IJN.S161031

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Govarthanan Muthusamy

Peer reviewer comments 3

Editor who approved publication: Prof. Dr. Thomas J Webster


Essraa A Hussein,1 Moustafa M Zagho,1 Gheyath K Nasrallah,2,3 Ahmed A Elzatahry1

1Materials Science and Technology Program, College of Arts and Sciences, Qatar University, Doha, Qatar; 2Department of Biomedical Science, College of Health Sciences, Qatar University, Doha, Qatar; 3Biomedical Research Center, Qatar University, Doha, Qatar

Abstract: Being a non-invasive and relatively safe technique, photothermal therapy has attracted a lot of interest in the cancer treatment field. Recently, nanostructure technology has entered the forefront of cancer therapy owing to its ability to absorb near-infrared radiation as well as efficient light to heat conversion. In this study, key nanostructures for cancer therapy including gold nanoparticles, magnetite iron oxide nanoparticles, organic nanomaterials, and novel two-dimensional nanoagents such as MXenes are discussed. Furthermore, we briefly discuss the characteristics of the nanostructures of these photothermal nanomaterial agents, while focusing on how nanostructures hold potential as cancer therapies. Finally, this review offers promising insight into new cancer therapy approaches, particularly in vivo and in vitro cancer treatments.

Keywords: photothermal therapy, nanostructures, near-infrared, plasmonic, cancer therapy

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