Recent advance on the antitumor and antioxidant activity of grape seed extracts
Fengmei Zhu, Bin Du, Jun Li
College of Food Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao, Hebei Province, People's Republic of China
Abstract: The grape pomace (including seeds and stems) poses potential disposal and pollution problems along with loss of valuable biomass and nutrients. The utilization of grape seeds processing as a source of functional ingredients is a promising field. Grape seed extract provides a concentrated source of polyphenols. Grape seed extract is known as an effective antioxidant that protects the body from premature aging and disease. A number of phytochemicals including resveratrol, proanthocyanidins, etc, have demonstrated significant benefits in cancer chemoprevention. In this review, we summarize the existing knowledge on the antitumor and antioxidant activity of grape seeds polyphenols.
Keywords: grape seed, antitumor activity, antioxidant activity, polyphenol, proanthocyanidin
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