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Recent advance on the antitumor and antioxidant activity of grape seed extracts

Authors Zhu F, Du B, Li J

Received 19 January 2015

Accepted for publication 1 April 2015

Published 8 May 2015 Volume 2015:7 Pages 63—67

DOI https://doi.org/10.2147/IJWR.S76162

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Roger Pinder


Fengmei Zhu, Bin Du, Jun Li

College of Food Science and Technology, Hebei Normal University of Science and Technology, Qinhuangdao, Hebei Province, People's Republic of China

Abstract: The grape pomace (including seeds and stems) poses potential disposal and pollution problems along with loss of valuable biomass and nutrients. The utilization of grape seeds processing as a source of functional ingredients is a promising field. Grape seed extract provides a concentrated source of polyphenols. Grape seed extract is known as an effective antioxidant that protects the body from premature aging and disease. A number of phytochemicals including resveratrol, proanthocyanidins, etc, have demonstrated significant benefits in cancer chemoprevention. In this review, we summarize the existing knowledge on the antitumor and antioxidant activity of grape seeds polyphenols.

Keywords: grape seed, antitumor activity, antioxidant activity, polyphenol, proanthocyanidin

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