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Radio contrast imaging for continuous epidural infusion in humans: a report of three cases

Authors Matsusaki T, Kaku R, Ono D, Taniguchi A, Morimatsu H

Received 5 November 2018

Accepted for publication 30 January 2019

Published 25 March 2019 Volume 2019:12 Pages 1077—1082

DOI https://doi.org/10.2147/JPR.S193500

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Dr Michael E Schatman


Takashi Matsusaki, Ryuji Kaku, Daisuke Ono, Arata Taniguchi, Hiroshi Morimatsu

Department of Anesthesiology and Resuscitology, Okayama University Hospital, Okayama, Japan

Abstract: There are no reports of human research on continuous epidural contrast injection, and there are no definite methods to investigate the spread of drugs injected continuously into the epidural space. We investigated the feasibility of continuous epidural contrast injection in patients undergoing computed tomography (CT)-guided therapy. In this study, a combination of a contrast agent mixed with 0.75% ropivacaine was used as the test drug. The main outcome evaluated was the feasibility of continuous epidural contrast imaging by CT scan following epidural injection of a contrast agent with 0.75% ropivacaine. We studied three patients who underwent CT-guided procedures and found that continuous epidural contrast injection was possible without any deleterious effects, such as an allergic reaction. The spread of the contrast agent was not consistent with the level of the clinical analgesic effect. Continuous epidural contrast injection is a feasible procedure. The results of our study might contribute to future research on continuous epidural contrast administration, as well as provide patients with superior analgesia.

Keywords: continuous epidural contrast, 3D-CT scan, spread of epidural analgesia


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