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Quality of life of patients with proximal humerus metastasis treated with cement spacer

Authors Guo W, Gao X, Wang D, Wang T, Tang L, Wang Y, Liu B

Received 12 June 2019

Accepted for publication 23 August 2019

Published 17 September 2019 Volume 2019:11 Pages 8499—8506

DOI https://doi.org/10.2147/CMAR.S219178

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 3

Editor who approved publication: Dr Eileen O'Reilly


Wen Guo,1,* Xin Gao,2,* Dongsheng Wang,2,* Tao Wang,2 Liang Tang,2 Yao Wang,2 Bin Liu3,*

1Department of Orthopedics, Taizhou Peopleʼs Hospital, Taizhou 225300, Jiangsu, People’s Republic of China; 2Orthopaedic Oncology Center, Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai 200000, People’s Republic of China; 3Department of Bone and Soft Tissue Neurosurgery, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, Guangxi, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Wen Guo
Department of Orthopedics, Taizhou People’s Hospital, No.366 Taihu Road, Taizhou 225300, Jiangsu, People’s Republic of China
Email guowen142623@163.com

Bin Liu
Department of Bone and Soft Tissue Neurosurgery, Affiliated Tumor Hospital of Guangxi Medical University, 71 He Di Road, Nanning 530021, Guangxi, People’s Republic of China
Email liubin1982Dr@163.com

Purpose: The goal of this study was to determine whether the surgery using cement spacer could improve the quality of life of patients with proximal humerus metastasis.
Patients and methods: This is a retrospective study. The study included 34 patients who had been treated for proximal humerus metastasis between January 2010 and June 2014. The patients were divided into surgical and non-surgical group depending on whether they underwent cement spacer surgery. The patient’s quality of life (QOL) assessment is scheduled at five points—at the initial diagnosis (baseline) and at 1 month, 3 months, 6 months, and 9 months of follow-up. Evaluation tool is Functional Assessment of Cancer Therapy-General (FACT-G) questionnaire.
Results: A total of 34 patients, including 15 patients in the surgery group and 19 patients in the non-surgery group, were enrolled in this retrospective study. In the end, 22 patients finished all evaluations, including 11 patients in the surgical group and 11 patients in the non-surgery group. At the completion of the study, 22 patients had died, including 8 patients in the surgery group and 14 patients in the non-surgery group. After surgical using the cement spacer, the QOL scores of patients at each follow-up point were significantly higher than that of preoperative scores. These scores were also higher than those of the non-surgery group.
Conclusion: The current study indicated that surgical treatment using the cement spacer could upgrade and maintain quality of life for patients with proximal humerus metastasis in the 9-month assessment.

Keywords: cement spacer, proximal humerus metastasis, quality of life, palliative treatment

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