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Psychiatric symptoms in glioma patients: from diagnosis to management

Authors Boele F, Rooney A, Grant R, Klein M

Received 19 March 2015

Accepted for publication 10 April 2015

Published 10 June 2015 Volume 2015:11 Pages 1413—1420


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Roger Pinder

Florien W Boele,1 Alasdair G Rooney,2 Robin Grant,2 Martin Klein1

1Department of Medical Psychology, VU University Medical Center, Amsterdam, the Netherlands; 2Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK

Abstract: Patients with primary intrinsic brain tumors can experience neurological, cognitive, and psychiatric symptoms that greatly affect daily life. In this review, we focus on changes in personality and behavior, mood issues, hallucinations, and psychosis, because these are either difficult to recognize, to treat, or are understudied in scientific literature. Neurobehavioral symptoms are common, often multiple, and causation can be multifactorial. Although different symptoms sometimes require a different treatment approach, we advise a comprehensive treatment approach, including pharmacological treatment and/or psychotherapy where appropriate. Further research is needed to obtain a better estimate of the prevalence of psychiatric symptoms in glioma patients, and the extent to which these affect everyday functioning and family life.

Keywords: glioma, psychiatry, personality, mood, hallucinations, psychosis

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