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Prospective Studies of Minimally Invasive Glaucoma Surgeries: Systematic Review and Quality Assessment

Authors Rosdahl JA, Gupta D

Received 23 November 2019

Accepted for publication 24 December 2019

Published 24 January 2020 Volume 2020:14 Pages 231—243

DOI https://doi.org/10.2147/OPTH.S239772

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Jullia A Rosdahl, Divakar Gupta

Department of Ophthalmology, Duke University, Durham, NC 27710, USA

Correspondence: Jullia A Rosdahl
Department of Ophthalmology, Duke University, 2351 Erwin Road, DUMC 3802, Durham, NC 27710, USA
Tel +1 919-684-8850
Fax +1 919-681-8267
Email Jullia.rosdahl@duke.edu

Abstract: Glaucoma is a common blinding disease; while there is no cure, effective treatments include medications, laser, and incisional surgery. There is significant interest from patients and doctors to develop safer surgical options throughout the spectrum of disease, to minimize treatment burden in mild glaucoma patients and to minimize risk of complications in patients needing more aggressive treatment. Surgical procedures called Minimally or Micro-Invasive Glaucoma Surgery (MIGS) are growing in popularity. Eighty-seven prospective studies on MIGS were identified and assessed for quality. Most (74%) did not have a control group. Twelve of the highest quality were reviewed. MIGS procedures appeared to have fewer complications, and lowered intraocular pressure, and reduced medication use. Studies were limited by small sample size, narrow spectrum of glaucomatous disease, and/or conflicts of interest. There is a need for high quality, independently funded and performed, comparative studies on the MIGS to help make treatment decisions.

Keywords: MIGS, angle surgery, ab interno, microinvasive, glaucoma treatment

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