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Progress in immunocytochemical staining for cervical cancer screening

Authors Sun H, Shen K, Cao D

Received 4 December 2018

Accepted for publication 23 January 2019

Published 22 February 2019 Volume 2019:11 Pages 1817—1827

DOI https://doi.org/10.2147/CMAR.S195349

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 2

Editor who approved publication: Dr Antonella D'Anneo


Hengzi Sun, Keng Shen, Dongyan Cao

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Abstract: Cervical cancer is one of the most common gynecological malignancies. In recent years, the implementation of cervical cancer screening has resulted in the effective control of cervical cancer incidence. However, many deficiencies still exist in the current screening techniques and strategies. With advancements in cervical cancer screening research, immunochemical staining to determine cervical cytology has shown a broader application prospect in the early screening for cervical cancer, especially for triage in cervical cancer screening.

Keywords: HSIL, dual staining, p16, Ki-67, triage strategy, colposcopy referral

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