Prognosis of the outcome of severe diabetic foot ulcers with multidisciplinary care
Received 19 November 2018
Accepted for publication 20 February 2019
Published 2 May 2019 Volume 2019:12 Pages 349—359
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Scott Fraser
Luz Marina Alfonso Dutra,1 Manuela Costa Melo,2 Mirian Conceição Moura,3 Lílian Assumpção Paes Leme,4 Marta Rodrigues De Carvalho,3 Andre Neves Mascarenhas,4 Maria Rita Carvalho Garbi Novaes1
1Department of Health Sciences, University of Brasília, Brasília, Federal District, Brazil; 2Departament of Nursing, Higher School of Health Sciences, Brasília, Federal District, Brazil; 3Department of Medicine, Higher School of Sciences and Hospital of the Secretary of Health of the Federal District, Clinical Neurophysiologist, Brasília, Federal District, Brazil; 4Department of Endocrinology, Regional Hospital of Asa Norte, Brasília, Federal District, Brazil
Background: Approximately 2–4% of individuals worldwide with diabetes mellitus have foot ulcers. This study aims to assess the factors affecting the outcomes of severe foot ulcers in diabetic individuals.
Methods: An analytical prospective cohort study was conducted from March 1st, 2015, to March 1st, 2017. A total of 34 individuals was selected. The study included patients with foot ulcers below the ankle who were at risk of amputation. All tests used a <5% level of significance and confidence interval of 95%. A Pearson’s chi-squared test and binary multiple regression were performed to assess the factors related to healing.
Results: Only 11.7% of the individuals required amputation; ulcers classified as 2/B according to the University of Texas Diabetic Foot Ulcer Classification System healed before the 1/B ulcers. Neuropathic ulcers were the most prevalent (58.8%); 61.8% healed after 1 year. Most of the individuals were overweight, 47.1% had reduced glomerular filtration rates, and 78.8% had glycated hemoglobin >7%. Body mass index and osteomyelitis were the two significant variables in logistic regression.
Conclusions: In this study, osteomyelitis was the main complication related to the risk of amputation, and elevated body mass index and osteomyelitis were the significant factors that induced a slower healing time.
Keywords: diabetes mellitus, diabetic foot, diabetes complications, multidisciplinary care
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]