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Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies

Authors Jin Z, Gan TJ, Bergese SD

Received 5 October 2020

Accepted for publication 5 December 2020

Published 31 December 2020 Volume 2020:16 Pages 1305—1317

DOI https://doi.org/10.2147/TCRM.S256234

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Garry Walsh


Zhaosheng Jin,1 Tong J Gan,1 Sergio D Bergese1,2

1Department of Anesthesiology, Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA; 2Department of Neurological Surgery, Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA

Correspondence: Sergio D Bergese
Stony Brook University Health Science Center, Stony Brook, NY 11794-8480, USA
Tel +1 631-444-2975
Email Sergio.Bergese@stonybrookmedicine.edu

Abstract: Postoperative nausea and vomiting is one of the most frequent adverse events after surgery and anesthesia. It is distressing for the patient and can lead to other postoperative complications. Management of PONV involves a framework of risk assessment, multimodal risk reduction, and prophylactic measures, as well as prompt rescue treatment. There has been a significant paradigm shift in the approach towards PONV prevention. There have also been several emerging therapeutic options for PONV prophylaxis and treatment. In this review, we will discuss the up-to-date PONV management guidelines and highlight novel therapeutic options which have emerged in the last few years.

Keywords: antiemetics, enhanced recovery after surgery, postoperative care, postoperative nausea and vomiting

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