Back to Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 10 » Issue 1

Prevalence of chronic obstructive pulmonary disease in asymptomatic smokers

Authors Sansores RH, Velázquez-Uncal M, Pérez-Bautista O, Villalba-Caloca J, Falfán-Valencia R, Ramírez-Venegas A

Received 3 July 2015

Accepted for publication 19 September 2015

Published 2 November 2015 Volume 2015:10(1) Pages 2357—2363

DOI https://doi.org/10.2147/COPD.S91742

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Professor Hsiao-Chi Chuang

Peer reviewer comments 3

Editor who approved publication: Dr Richard Russell

Raúl H Sansores, Mónica Velázquez-Uncal, Oliver Pérez-Bautista, Jaime Villalba-Caloca, Ramcés Falfán-Valencia, Alejandra Ramírez-Venegas

Tobacco Smoking and COPD Research Department, National Institute of Respiratory Diseases, Ismael Cosio Villegas, Mexico City, Mexico

Background: Physicians do not routinely recommend smokers to undergo spirometry unless they are symptomatic.
Objective: To test the hypothesis that there are a significant number of asymptomatic smokers with chronic obstructive pulmonary disease (COPD), we estimated the prevalence of COPD in a group of asymptomatic smokers.
Methods: Two thousand nine hundred and sixty-one smokers with a cumulative consumption history of at least 10 pack-years, either smokers with symptoms or smokers without symptoms (WOS) were invited to perform a spirometry and complete a symptom questionnaire.
Results: Six hundred and thirty-seven (21.5%) smokers had no symptoms, whereas 2,324 (78.5%) had at least one symptom. The prevalence of COPD in subjects WOS was 1.5% when considering the whole group of smokers (45/2,961) and 7% when considering only the group WOS (45/637). From 329 smokers with COPD, 13.7% were WOS. Subjects WOS were younger, had better lung function and lower cumulative consumption of cigarettes, estimated as both cigarettes per day and pack-years. According to severity of airflow limitation, 69% vs 87% of subjects were classified as Global Initiative for Chronic Obstructive Lung Disease stages I–II in the WOS and smokers with symptoms groups, respectively (P<0.001). A multivariate analysis showed that forced expiratory volume in 1 second (mL) was the only predictive factor for COPD in asymptomatic smokers.
Conclusion: Prevalence of COPD in asymptomatic smokers is 1.5%. This number of asymptomatic smokers may be excluded from the benefit of an “early” intervention, not just pharmacological but also from smoking cessation counseling. The higher forced expiratory volume in 1 second may contribute to prevent early diagnosis.

Keywords: COPD, asymptomatic smokers, early diagnosis

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Readers of this article also read:

Switching treatments in COPD: implications for costs and treatment adherence

Braido F, Lavorini F, Blasi F, Baiardini I, Canonica GW

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:2601-2608

Published Date: 3 December 2015

The utility of inflammatory markers to predict readmissions and mortality in COPD cases with or without eosinophilia

Duman D, Aksoy E, Agca MC, Kocak ND, Ozmen I, Akturk UA, Gungor S, Tepetam FM, Eroglu SA, Oztas S, Karakurt Z

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:2469-2478

Published Date: 11 November 2015

COPD: it is time to change!

Tantucci C, Pini L

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:2451-2457

Published Date: 11 November 2015

Increased serum TRAIL and DR5 levels correlated with lung function and inflammation in stable COPD patients

Wu YQ, Shen YC, Zhang JL, Wan C, Wang T, Xu D, Yang T, Wen FQ

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:2405-2412

Published Date: 6 November 2015

Pulmonary hemodynamic profile in chronic obstructive pulmonary disease [Corrigendum]

Portillo K, Torralba Y, Blanco I, Burgos F, Rodriguez-Roisin R, Rios J, Roca J, Barberà JA

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:2377-2378

Published Date: 4 November 2015

The importance of inhaler devices: the choice of inhaler device may lead to suboptimal adherence in COPD patients

Darbà J, Ramírez G, Sicras A, Francoli P, Torvinen S, Sánchez-de la Rosa R

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:2335-2345

Published Date: 29 October 2015