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Prevalence of 25-hydroxyvitamin D deficiency in healthy personnel from an academic institution of an urban area in Costa Rica

Authors Gamboa-Gamboa T, Abarca-Soto G, José G Jiménez-Montero

Received 13 June 2015

Accepted for publication 23 August 2015

Published 12 October 2015 Volume 2015:5 Pages 135—140


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Mingzhao Xing

Tatiana Gamboa-Gamboa,1 Gabriel Abarca-Soto,2 José G Jiménez-Montero3,4

1Department of Research and Nutrition, Universidad de Ciencias Médicas, San José, Costa Rica; 2Department of Research, School of Medicine, Universidad de Ciencias Médicas, San José, Costa Rica; 3Department of Postgraduate Studies, Universidad de Ciencias Médicas, San José, Costa Rica; 4Department of Endocrinology, Hospital CIMA, San José, Costa Rica

Objective: The aim of this study was to determine 25-hydroxyvitamin D concentrations in healthy employees of the Universidad de Ciencias Médicas, Costa Rica.
Methods: Levels of 25-hydroxyvitamin D, calcium, phosphorus, intact parathyroid hormone (iPTH), and creatinine were measured in 80 people. Solar ultraviolet radiation exposure and 25-hydroxyvitamin D intake were estimated using a previously designed questionnaire. Participants were 52 women aged (mean ± standard deviation) 35.8±10.0 years old, body mass index of 27.1±5.9 kg/m2, and 26 men aged 36.4±10.8 years old, body mass index of 27.5±5.0 kg/m2.
Results: All participants were normocalcemic, eight females were postmenopausal, three were hypertensive; none had renal, gastrointestinal, or thyroid disease. The level of 25-hydroxyvitamin D was 23.9±7.0 ng/dL and iPTH 40.1±17.5 pg/dL. A level of 25-hydroxyvitamin D $30 ng/dL was seen in 17% of the population. The eight participants with iPTH higher than 67 ng/dL, had 25-hydroxyvitamin D of 18.9±4.8 ng/dL. Two participants who received 25-hydroxyvitamin D and calcium supplements were excluded.
Conclusion: The 25-hydroxyvitamin D insufficiency and deficiency found in healthy employees from an academic center in Costa Rica may be due to working long hours in-doors and solar ultraviolet radiation exposure. It is unknown whether secondary hyperparathyroidism seen in nearly 10% of this population, may have long-term effects on bone health.

Keywords: vitamin D deficiency, osteoporosis, secondary hyperparathyroidism, bone metabolism

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