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Prevalence and determinants of metabolic syndrome: a cross-sectional survey of general medical outpatient clinics using National Cholesterol Education Program-Adult Treatment Panel III criteria in Botswana

Authors Omech B, Tshikuka J, Mwita J, Tsima B, Nkomazana O, Amone-P'Olak K

Received 22 March 2016

Accepted for publication 2 June 2016

Published 30 August 2016 Volume 2016:9 Pages 273—279

DOI https://doi.org/10.2147/DMSO.S109007

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Lucy Goodman

Peer reviewer comments 4

Editor who approved publication: Professor Ming-Hui Zou


Bernard Omech,1 Jose-Gaby Tshikuka,2 Julius C Mwita,1 Billy Tsima,2 Oathokwa Nkomazana,3 Kennedy Amone-P’Olak4

1Department of Internal Medicine, 2Department of Family Medicine and Public Health, 3Department of Surgery, 4Department of Psychology, University of Botswana, Gaborone, Botswana

Background:
Low- and middle-income countries, including Botswana, are facing rising prevalence of obesity and obesity-related cardiometabolic complications. Very little information is known about clustering of cardiovascular risk factors in the outpatient setting during routine visits. We aimed to assess the prevalence and identify the determinants of metabolic syndrome among the general outpatients’ attendances in Botswana.
Methods: A cross-sectional study was conducted from August to October 2014 involving outpatients aged ≥20 years without diagnosis of diabetes mellitus. A precoded questionnaire was used to collect data on participants’ sociodemographics, risk factors, and anthropometric indices. Fasting blood samples were drawn and analyzed for glucose and lipid profile. Metabolic syndrome was assessed using National Cholesterol Education Program-Adult Treatment Panel III criteria.
Results: In total, 291 participants were analyzed, of whom 216 (74.2%) were females. The mean age of the total population was 50.1 (±11) years. The overall prevalence of metabolic syndrome was 27.1% (n=79), with no significant difference between the sexes (female =29.6%, males =20%, P=0.11). A triad of central obesity, low high-density lipoprotein-cholesterol, and elevated blood pressure constituted the largest proportion (38 [13.1%]) of cases of metabolic syndrome, followed by a combination of low high-density lipoprotein, elevated triglycerides, central obesity, and elevated blood pressure, with 17 (5.8%) cases. Independent determinants of metabolic syndrome were antihypertensive use and increased waist circumference.
Conclusion: Metabolic syndrome is highly prevalent in the general medical outpatients clinics. Proactive approaches are needed to screen and manage cases targeting its most important predictors.

Keywords:
metabolic syndrome, determinants, general medical outpatient clinics, Botswana

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