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Presumed bilateral branch retinal vein occlusions secondary to antiepileptic agents

Authors Hussain R, Banerjee

Published 13 May 2011 Volume 2011:5 Pages 609—611

DOI https://doi.org/10.2147/OPTH.S17754

Review by Single-blind

Peer reviewer comments 2


Rumana N Hussain, Somnath Banerjee
Leicester Royal Infirmary, Leicester, UK

Abstract: A 61-year-old man presented to the ophthalmology department having developed bilateral branch retinal vein occlusions. Baseline blood tests revealed no abnormality; however, subsequent investigations showed a raised plasma homocysteine (HC) level. The patient has been treated for refractory epilepsy for a number of years. Although antiepileptic medications have been shown to reduce folate levels and result in a raised HC level, this has not previously been shown to be to a level causing a retinal vascular event.

Keywords: homocysteine, branch vein occlusions

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