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Pregnancy in heart transplant recipients – current perspectives

Authors Watson WD, Bhagra SK, Bhagra CJ

Received 10 May 2019

Accepted for publication 1 August 2019

Published 23 August 2019 Volume 2019:11 Pages 29—38

DOI https://doi.org/10.2147/TRRM.S188281

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Nicola Ludin

Peer reviewer comments 2

Editor who approved publication: Professor Qing Yi


William D Watson,1 Sai K Bhagra,2 Catriona J Bhagra3,4

1Division of Cardiovascular Medicine, University of Oxford, Oxford, UK; 2Transplant Unit, Royal Papworth Hospital, Cambridge, UK; 3Department of Cardiology, Addenbrooke’s Hospital, Cambridge, UK; 4Department of Cardiology, Royal Papworth Hospital, Cambridge, UK

Correspondence: Catriona J Bhagra
Department of Cardiology, Addenbrooke’s Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK
Email catriona.bhagra@nhs.net

Abstract: Successful pregnancy with a live birth and preserved graft function is possible in women following cardiac transplantation but requires careful assessment and planning in conjunction with the co-ordinated care of a specialist multidisciplinary team. Pregnancy poses significant risks to the mother, graft and foetus; these include the challenges of managing immunosuppression to avoid rejection whilst balancing the risks to the foetus from potentially teratogenic medication. This article aims to provide a contemporary perspective on the issues pertaining to pregnancy in heart transplant recipients; describing the pre-conception, pre-partum, intrapartum and postpartum management in this unique group of women.

Keywords: pregnancy, cardiac transplantation, heart transplant
 

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