Back to Journals » International Journal of General Medicine » Volume 14

Pre-Exposure Prophylaxis for COVID-19 in Pregnant Women

Authors Fesler MC, Stricker RB

Received 3 December 2020

Accepted for publication 13 January 2021

Published 26 January 2021 Volume 2021:14 Pages 279—284

DOI https://doi.org/10.2147/IJGM.S295627

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Melissa C Fesler,1,2 Raphael B Stricker1,2

1Alan E. Beer Medical Center for Reproductive Immunology, Los Gatos, CA, USA; 2Union Square Medical Associates, San Francisco, CA, USA

Correspondence: Raphael B Stricker
Union Square Medical Associates, 450 Sutter Street, Suite 1504, San Francisco, CA 94108, USA
Tel +1 415-399-1035
Email rstricker@usmamed.com

Abstract: Pregnant women are at higher risk for developing severe complications of COVID-19 including preterm delivery, respiratory failure, and death. Although vaccines to prevent COVID-19 are being developed, pregnant women are not included in the current COVID-19 vaccine trials and initially this population may not be eligible for COVID-19 vaccines due to lack of safety testing in pregnancy. As an alternate approach, we discuss the concept of pre-exposure prophylaxis (PrEP) using medications that are approved for use in pregnant women to prevent gestational problems and severe illness in this high-risk population. In particular, the use of hydroxychloroquine PrEP affords a safe and readily available means to avoid COVID-19 complications in pregnancy.

Keywords: COVID-19, SARS-CoV-2, pregnancy, pre-exposure prophylaxis, hydroxychloroquine, vaccine

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]