Back to Journals » Therapeutics and Clinical Risk Management » Volume 4 » Issue 4

Postoperative mortality after inpatient surgery: Incidence and risk factors

Authors Karamarie Fecho, Anne T Lunney, Philip G Boysen, Peter Rock, Edward A Norfleet

Published 8 August 2008 Volume 2008:4(4) Pages 681—688

DOI https://doi.org/10.2147/TCRM.S2735

Karamarie Fecho1, Anne T Lunney1, Philip G Boysen1, Peter Rock2, Edward A Norfleet1

1Department of Anesthesiology, School of Medicine, University of North Carolina, Chapel Hill, NC, USA; 2Department of Anesthesiology, University of Maryland, Baltimore, MD, USA

Purpose: This study determined the incidence of and identified risk factors for 48 hour (h) and 30 day (d) postoperative mortality after inpatient operations.

Methods: A retrospective cohort study was conducted using Anesthesiology’s Quality Indicator database as the main data source. The database was queried for data related to the surgical procedure, anesthetic care, perioperative adverse events, and birth/death/operation dates. The 48 h and 30 d cumulative incidence of postoperative mortality was calculated and data were analyzed using Chi-square or Fisher’s exact test and generalized estimating equations.

Results: The 48 h and 30 d incidence of postoperative mortality was 0.57% and 2.1%, respectively. Higher American Society of Anesthesiologists physical status scores, extremes of age, emergencies, perioperative adverse events and postoperative Intensive Care Unit admission were identified as risk factors. The use of monitored anesthesia care or general anesthesia versus regional or combined anesthesia was a risk factor for 30 d postoperative mortality only. Time under anesthesia care, perioperative hypothermia, trauma, deliberate hypotension and invasive monitoring via arterial, pulmonary artery or cardiovascular catheters were not identified as risk factors.

Conclusions: Our findings can be used to track postoperative mortality rates and to test preventative interventions at our institution and elsewhere.

Keywords: postoperative mortality, risk factors, operations, anesthesia, inpatient surgery

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF] 

 

Other articles by this author:

In-hospital resuscitation: opioids and other factors influencing survival

Karamarie Fecho, Freeman Jackson, Frances Smith, et al

Therapeutics and Clinical Risk Management 2009, 5:961-968

Published Date: 8 December 2009

Readers of this article also read:

Mesenchymal and induced pluripotent stem cells: general insights and clinical perspectives

Zomer HD, Vidane AS, Gonçalves NN, Ambrósio CE

Stem Cells and Cloning: Advances and Applications 2015, 8:125-134

Published Date: 28 September 2015

Modeling human influenza infection in the laboratory

Radigan KA, Misharin AV, Chi M, Scott Budinger GR

Infection and Drug Resistance 2015, 8:311-320

Published Date: 31 August 2015

The management of equine acute laminitis

Mitchell CF, Fugler LA, Eades SC

Veterinary Medicine: Research and Reports 2015, 6:39-47

Published Date: 22 December 2014

Cat amniotic membrane multipotent cells are nontumorigenic and are safe for use in cell transplantation

Vidane AS, Souza AF, Sampaio RV, Bressan FF, Pieri NC, Martins DS, Meirelles FV, Miglino MA, Ambrósio CE

Stem Cells and Cloning: Advances and Applications 2014, 7:71-78

Published Date: 27 August 2014

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010