Back to Journals » Neuropsychiatric Disease and Treatment » Volume 11

Posterior reversible encephalopathy syndrome in a woman with focal segmental glomerulosclerosis

Authors Chowdhary M, Kabbani A, Tobey D, Hope T

Received 5 March 2015

Accepted for publication 25 March 2015

Published 21 April 2015 Volume 2015:11 Pages 1111—1114

DOI https://doi.org/10.2147/NDT.S84010

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Roger Pinder

Mudit Chowdhary,1 Ahmad A Kabbani,1 Devon Tobey,1 Thomas D Hope2

1Department of Internal Medicine, Mercer University School of Medicine, Macon, GA, USA; 2Department of Neurology, Mercer University School of Medicine, Macon, GA, USA

Abstract: Posterior reversible encephalopathy syndrome (PRES) is a rare syndrome characterized by reversible vasogenic edema in the posterior hemispheres. PRES is most often attributed to primary hypertension, pre-eclampsia, and neurotoxicity secondary to immunosuppressants such as cyclosporine. Renal disease is an infrequent cause of PRES with a majority of cases occurring in adults with complete renal failure or in pediatric cases with underlying renal parenchymal disease and concurrent immunosuppressive therapy. Typical symptoms include seizure, headache, altered mental status, and visual disturbances. PRES is rarely associated with cerebral hemorrhage, and even less so with subarachnoid bleeds. Herein we report on a 25-year-old female with focal segmental glomerulosclerosis who developed PRES. The patient’s presentation was more severe as she presented with seizure, nephrotic syndrome, and subarachnoid hemorrhage. Computed tomography and magnetic resonance imaging with concurrent symptoms led us to the final diagnosis. The patient was treated with antihypertensives, diuretics, and corticosteroids and follow-up imaging revealed resolution of PRES. Our case illustrates that underlying kidney disease even without immunosuppressive agents should be added to the list of possible causes for PRES. Symptoms are reversible with treatment of underlying cause or offending agent.

Keywords: PRES, posterior reversible encephalopathy syndrome, focal segmental glomerulosclerosis, subarachnoid hemorrhage

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Other articles by this author:

Rapidly progressive stage IVB mycosis fungoides treated with low-dose total skin electron beam therapy

Chowdhary M, Kabbani AA, Rimtepathip P, Cole Jr DA, Cohen DJ

OncoTargets and Therapy 2015, 8:1597-1601

Published Date: 1 July 2015

Canagliflozin-induced pancreatitis: a rare side effect of a new drug

Chowdhary M, Kabbani AA, Chhabra A

Therapeutics and Clinical Risk Management 2015, 11:991-994

Published Date: 26 June 2015

Superior mesenteric artery syndrome: a unique complication following carboplatin-based chemotherapy

Chowdhary M, Pansuria HP, Farooqi B, Goyal H

International Medical Case Reports Journal 2015, 8:55-58

Published Date: 17 February 2015

Readers of this article also read:

Emerging and future therapies for hemophilia

Carr ME, Tortella BJ

Journal of Blood Medicine 2015, 6:245-255

Published Date: 3 September 2015

Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles

Prozorova GF, Pozdnyakov AS, Kuznetsova NP, Korzhova SA, Emel’yanov AI, Ermakova TG, Fadeeva TV, Sosedova LM

International Journal of Nanomedicine 2014, 9:1883-1889

Published Date: 16 April 2014

Methacrylic-based nanogels for the pH-sensitive delivery of 5-Fluorouracil in the colon

Ashwanikumar N, Kumar NA, Nair SA, Kumar GS

International Journal of Nanomedicine 2012, 7:5769-5779

Published Date: 15 November 2012

A novel preparation method for silicone oil nanoemulsions and its application for coating hair with silicone

Hu Z, Liao M, Chen Y, Cai Y, Meng L, Liu Y, Lv N, Liu Z, Yuan W

International Journal of Nanomedicine 2012, 7:5719-5724

Published Date: 12 November 2012

Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy

Deepa G, Thulasidasan AK, Anto RJ, Pillai JJ, Kumar GS

International Journal of Nanomedicine 2012, 7:4077-4088

Published Date: 27 July 2012

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010