Back to Journals » Clinical Interventions in Aging » Volume 10

Physical activity and all-cause mortality among older Brazilian adults: 11-year follow-up of the Bambuí Health and Aging Study

Authors Ramalho JRO, Mambrini JVM, César CC, de Oliveira CM, Oliveira Araújo Firmo J, Lima-Costa MF, Viana Peixoto S

Received 19 September 2014

Accepted for publication 25 October 2014

Published 16 April 2015 Volume 2015:10 Pages 751—758


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Richard Walker

Juciany RO Ramalho,1 Juliana VM Mambrini,1 Cibele C César,1,2 César M de Oliveira,3 Josélia OA Firmo,1 Maria Fernanda Lima-Costa,1 Sérgio V Peixoto1,4

1Rene Rachou Research Center, Oswaldo Cruz Foundation, 2Department of Statistics, Federal University of Minas Gerais, Belo Horizonte, Brazil; 3Research Department of Epidemiology and Public Health, University College London, London, UK; 4Nursing School, Federal University of Minas Gerais, Belo Horizonte, Brazil

Objective: To investigate the association between physical activity (eg, energy expenditure) and survival over 11 years of follow-up in a large representative community sample of older Brazilian adults with a low level of education. Furthermore, we assessed sex as a potential effect modifier of this association.
Materials and methods: A population-based prospective cohort study was conducted on all the ≥60-year-old residents in Bambuí city (Brazil). A total of 1,606 subjects (92.2% of the population) enrolled, and 1,378 (85.8%) were included in this study. Type, frequency, and duration of physical activity were assessed in the baseline survey questionnaire, and the metabolic equivalent task tertiles were estimated. The follow-up time was 11 years (1997–2007), and the end point was mortality. Deaths were reported by next of kin during the annual follow-up interview and ascertained through the Brazilian System of Information on Mortality, Brazilian Ministry of Health. Hazard ratios (95% confidence intervals [CIs]) were estimated by Cox proportional-hazard models, and potential confounders were considered.
Results: A statistically significant interaction (P<0.03) was found between sex and energy expenditure. Among older men, increases in levels of physical activity were associated with reduced mortality risk. The hazard ratios were 0.59 (95% CI 0.43–0.81) and 0.47 (95% CI 0.34–0.66) for the second and third tertiles, respectively. Among older women, there was no significant association between physical activity and mortality.
Conclusion: It was possible to observe the effect of physical activity in reducing mortality risk, and there was a significant interaction between sex and energy expenditure, which should be considered in the analysis of this association in different populations.

physical activity, mortality, sex, elderly

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]