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Pharmacological treatment of neuropathic pain in older persons

Authors Haslam C, Nurmikko T 

Published 7 March 2008 Volume 2008:3(1) Pages 111—120


Clair Haslam1, Turo Nurmikko2

1The Walton Centre for Neurology and Neurosurgery, Liverpool, England, UK; 2The Pain Research Institute, Division of Neurological Science, University of Liverpool, Liverpool, England, UK

Abstract: Interest and research into the mechanisms and treatment of neuropathic pain have increased during recent years, but current treatment is still far from satisfactory (Dworkin et al 2003; Attal et al 2006). The European Federation of Neurological Societies (EFNS) Task Force recently published guidelines for the pharmacological treatment of neuropathic pain (Attal et al 2006). However, no particular consideration is given as to how the recommendations are applicable to the elderly population. This paper will review the guidelines in relation to this population and evaluate the existing evidence relating to the use of these drugs in older persons.

Keywords: neuropathic pain, elderly, anticonvulsants, antidepressants, opioids, tramadol, lidocaine patch/plaster, capsaicin

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