Menu
Back to Journals » Orthopedic Research and Reviews » Volume 3
Perspectives on the clinical utility of allografts for bone regeneration within osseous defects: a narrative review
Published 5 April 2011 Volume 2011:3 Pages 31—37
DOI https://doi.org/10.2147/ORR.S18397
Review by Single anonymous peer review
Peer reviewer comments 4
Larry E Miller1,2, Jon E Block2
1Miller Scientific Consulting, LLC, Flagstaff, AZ, USA; 2Jon E. Block, Ph.D., Inc., San Francisco, CA, USA
Abstract: A variety of bone grafts and bone graft substitutes is available for treatment of osseous defects although adequate reconstruction of the residual void following fracture, arthroplasty, or tumor/cyst resection remains a therapeutic challenge. This narrative review evaluates the peer-reviewed literature and examines relevant outcomes in patients treated with bone grafts and bone graft substitutes for surgical management of osseous defects. Although autograft, xenograft, and ceramic bone graft substitutes are used for a variety of orthopedic applications, they have distinct limitations in clinical practice. Bone allograft material is a safe and effective adjunct to treatment of osseous defects.
Keywords: allograft, bone graft, osseous defect
© 2011 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.
By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.