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Paraganglioma of the vagina: a case report and review of the literature

Authors Cai T, Li Y, Jiang Q, Wang D, Huang Y

Received 10 February 2014

Accepted for publication 6 April 2014

Published 10 June 2014 Volume 2014:7 Pages 965—968

DOI https://doi.org/10.2147/OTT.S62174

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2


Tao Cai,1 Yucong Li,2 Qingming Jiang,3 Dong Wang,2 Yu Huang2

1Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, 2Department of Gynecologic Oncology, 3Department of Pathology, Chongqing Cancer Research Institute, Chongqing, People’s Republic of China

Abstract: Vaginal paraganglioma is a rare and unusual tumor occurring in the vaginal wall. It is a solitary primary paraganglioma, especially in atypical sites. Herein, we report an unusual case of a 17-year-old woman who had not experienced vomiting, or hypertension. She was found to have an immobile solid mass in the right side of her vaginal wall. Positron emission tomography/computed tomography scans revealed a well-defined solid ovoid mass adjacent to the bladder and pelvic floor. Tumor markers were within the normal range. A transient blood pressure increase occurred during the biopsy. After oral administration of antihypertensive drugs, surgery was performed to completely remove the mass. Histopathological examination indicated that it was a paraganglioma of the vagina. Repeat computed tomography examination did not reveal any local recurrence or distant metastasis during the 12-month follow-up period.

Keywords: vaginal paraganglioma, neuroendocrine tumor, clinical features, treatment


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