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Pain as a disease: an overview

Authors Raffaeli W, Arnaudo E

Received 5 April 2017

Accepted for publication 4 July 2017

Published 21 August 2017 Volume 2017:10 Pages 2003—2008

DOI https://doi.org/10.2147/JPR.S138864

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 4

Editor who approved publication: Dr Katherine Hanlon

William Raffaeli, Elisa Arnaudo

Fondazione ISAL Institute for Research on Pain, Torre Pedrera, Rimini, Italy

Abstract: The acknowledgment of pain as a pathologic entity in its own right remains debated. Notwithstanding the data showing the burden of pain as a disease, an ultimate recognition of the pathologic nature of this condition is lacking. In this study, we analyze the notion of pain as a disease through an historical overview of its several conceptualizations and report the main evidence supporting this notion. We believe that a clear definition of pain as a disease is necessary, especially considering the enormous global burden of this condition. Indeed, the recognition of pain as a definite pathologic state is crucial to raise awareness about this neglected global health problem and to promote the exploration of new specific therapeutic approaches.

Keywords: pain, disease, chronic pain, classification

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