Back to Browse Journals » Clinical and Experimental Gastroenterology » Volume 1

Oropharyngeal Crohn’s disease

Authors Rachid Mohamed, Robert Schultz, Richard N Fedorak

Published 4 December 2008 Volume 2008:1 Pages 15—18


Review by Single-blind

Peer reviewer comments 3

Rachid Mohamed, Robert Schultz, Richard N Fedorak

Division of Gastroenterology, University of Alberta, Edmonton, Alberta

Abstract: Crohn’s disease is a chronic inflammatory disease that can affect any part of the gastrointestinal tract. Classically the disease has a predilection for the distal small bowel and colon and presents with dominant symptoms of abdominal pain and diarrhea. This case report describes a 38-year-old woman with Crohn’s disease who presented with odynophagia. Direct visualization of the oropharynx revealed a large serpiginous Crohn’s disease ulcer. A precipitous drop in hemoglobin prompted a series of gastroenterologic investigations that confirmed both ileal and oropharyngeal Crohn’s disease. This manuscript describes the presentation of oropharyngeal Crohn’s and reviews previous reports and management options.

Keywords: Crohn’s disease, odynophagia, immunomodulatory therapy, oropharyngeal Crohn’s disease, aphthous ulcer, gastroscopy

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF] 


Readers of this article also read:

Hidden costs of antiretroviral treatment: the public health efficiency of drug packaging

Andreu-Crespo À, Llibre JM, Cardona-Peitx G, Sala-Piñol F, Clotet B, Bonafont-Pujol X

Drug Design, Development and Therapy 2015, 9:4287-4290

Published Date: 5 August 2015

Case-control association study of ABCB1 gene and major depressive disorder in a local Chinese Han population

Xie WW, Zhang L, Wu RR, Yu Y, Zhao JP, Li LH

Neuropsychiatric Disease and Treatment 2015, 11:1967-1971

Published Date: 4 August 2015

Optimal management of renal artery fibromuscular dysplasia

Gottsäter A, Lindblad B

Therapeutics and Clinical Risk Management 2014, 10:583-595

Published Date: 28 July 2014

Melanocytoma of the ciliary body misdiagnosed as iridodialysis

Kim M, Lee SJ

Clinical Ophthalmology 2014, 8:1051-1053

Published Date: 29 May 2014

Polyhydroxylated fullerene attenuates oxidative stress-induced apoptosis via a fortifying Nrf2-regulated cellular antioxidant defence system

Ye SF, Chen M, Jiang YQ, Chen ML, Zhou T, Wang YG, Hou ZQ, Ren L

International Journal of Nanomedicine 2014, 9:2073-2087

Published Date: 29 April 2014

Filament formation associated with spirochetal infection: a comparative approach to Morgellons disease

Middelveen MJ, Stricker RB

Clinical, Cosmetic and Investigational Dermatology 2011, 4:167-177

Published Date: 14 November 2011

Methylnaltrexone in the treatment of opioid-induced constipation

Beverley Greenwood-Van Meerveld, Kelly M Standifer

Clinical and Experimental Gastroenterology 2008, 1:49-58

Published Date: 14 December 2008

Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome

Albert Craig Lockhart, Elizabeth Harris, Bonnie J LaFleur, Nipun B Merchant, Mary Kay Washington, et al

Clinical and Experimental Gastroenterology 2008, 1:1-7

Published Date: 2 November 2008