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Orofacial pain management: current perspectives

Authors Romero-Reyes M, Uyanik JM

Received 29 August 2013

Accepted for publication 29 October 2013

Published 21 February 2014 Volume 2014:7 Pages 99—115

DOI https://doi.org/10.2147/JPR.S37593

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4


Marcela Romero-Reyes, James M Uyanik

Orofacial and Head Pain Service, Department of Oral and Maxillofacial Pathology Radiology and Medicine, New York University College of Dentistry, New York, NY, USA

Abstract: Some of the most prevalent and debilitating pain conditions arise from the structures innervated by the trigeminal system (head, face, masticatory musculature, temporomandibular joint and associated structures). Orofacial pain (OFP) can arise from different regions and etiologies. Temporomandibular disorders (TMD) are the most prevalent orofacial pain conditions for which patients seek treatment. Temporomandibular disorders include a number of clinical problems that involve the masticatory musculature, the temporomandibular joint (TMJ) or both. Trigeminal neuropathic pain conditions can arise from injury secondary to dental procedures, infection, neoplasias, or disease or dysfunction of the peripheral and/or central nervous system. Neurovascular disorders, such as primary headaches, can present as chronic orofacial pain, such as in the case of facial migraine, where the pain is localized in the second and third division of the trigeminal nerve. Together, these disorders of the trigeminal system impact the quality of life of the sufferer dramatically. A multidisciplinary pain management approach should be considered for the optimal treatment of orofacial pain disorders including both non-pharmacological and pharmacological modalities.

Keywords: pain, orofacial, neuropathic, TMD, trigeminal, headache

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