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Orbital plasmablastic lymphoma: a clinico-pathological correlation of a rare disease and review of literature

Authors Mulay K, Ali MJ, Reddy VA, Honavar SG

Received 18 September 2012

Accepted for publication 23 October 2012

Published 11 December 2012 Volume 2012:6 Pages 2049—2057

DOI https://doi.org/10.2147/OPTH.S38282

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Kaustubh Mulay,1 Mohammad Javed Ali,2 Vijay Anand Reddy,2 Santosh G Honavar2

1Ocular Pathology Service, LV Prasad Eye Institute, Hyderabad, Andhra Pradesh, India; 2Oncology Service, LV Prasad Eye Institute, Hyderabad, Andhra Padresh, India

Abstract: Ocular involvement by plasmablastic lymphoma is extremely rare with very few reports in the literature. Its morphological and immunological resemblance to plasma cell myeloma makes it a diagnostic challenge, while its clinical course, which is characterized by recurrence and death, makes therapy a challenge for clinicians. We present three cases of plasmablastic lymphoma, each of which has distinct clinicoradiological features, and we also review the literature on orbital plasmablastic lymphomas.

Keywords: plasmablastic lymphoma, ocular, myeloma, orbit

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