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Optimal management of type 2 diabetes in patients with increased risk of hypoglycemia

Authors Anderson M, Powell J, Campbell K, Taylor J

Received 19 December 2013

Accepted for publication 14 January 2014

Published 6 March 2014 Volume 2014:7 Pages 85—94

DOI https://doi.org/10.2147/DMSO.S48896

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3


Morgan Anderson,1 Jason Powell,2 Kendall M Campbell,3 James R Taylor2

1North Florida/South Georgia Veterans Health System, Malcom Randall VAMC, 2University of Florida, College of Pharmacy, Gainesville, 3The Center for Underrepresented Minorities in Academic Medicine, The Florida State University College of Medicine Tallahassee, FL, USA

Abstract: With the number of individuals diagnosed with type 2 diabetes on the rise, it has become more important to ensure these patients are effectively treated. The Centers for Disease Control and Prevention estimated that 8.3% of all Americans were diagnosed with diabetes in 2011 and this number will likely continue to rise. With lifestyle interventions, such as proper diet and exercise, continuing to be an essential component of diabetes treatment, more patients are requiring medication therapy to help them reach their therapeutic goals. It is important for the clinician, when determining the treatment strategy for these individuals, to find a balance between reaching treatment goals and limiting the adverse effects of the treatments themselves. Of all the adverse events associated with treatment of diabetes, the risk of hypoglycemia is one that most therapies have in common. This risk is often a limiting factor when attempting to aggressively treat diabetic patients. This manuscript will review how hypoglycemia is defined and categorized, as well as discuss the prevalence of hypoglycemia among the many different treatment options.

Keywords: type 2 diabetes, hypoglycemia


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