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Optimal management of muscle-invasive bladder cancer – a review

Authors Scarpato K, Morgans A, Moses K

Received 28 May 2015

Accepted for publication 30 July 2015

Published 4 September 2015 Volume 2015:7 Pages 143—151

DOI https://doi.org/10.2147/RRU.S73566

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Venkateshwar Madka

Peer reviewer comments 5

Editor who approved publication: Dr Jan Colli


Kristen R Scarpato,1 Alicia K Morgans,2 Kelvin A Moses1

1Department of Urologic Surgery, 2Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA

Abstract: Muscle-invasive bladder cancer is a complex disease requiring aggressive management. Patients are often older with comorbid conditions that impact treatment options. This review describes the available therapies for invasive urothelial carcinoma, including chemotherapy, radical extirpative surgery, and bladder-preserving strategies.

Keywords: bladder cancer, urothelial carcinoma, neoadjuvant chemotherapy, radical cystectomy

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