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Optic nerve sheath fenestration in cryptococcal meningitis

Authors Milman T, Mirani N, Turbin R

Published 12 September 2008 Volume 2008:2(3) Pages 637—639

DOI https://doi.org/10.2147/OPTH.S2096



Tatyana Milman1, Neena Mirani1,2, Roger E Turbin1

1Ophthalmology Department, Institute of Ophthalmology and Visual Science, 2Pathology Department, University Hospital, New Jersey Medical School, Newark, NJ, USA

Abstract: A patient with acquired immunodeficiency syndrome (AIDS) developed crytpococcal meningitis, complicated by papilledema and severe progressive visual loss despite medical therapy. Bilateral optic sheath fenestration resulted in significant improvement in vision and resolution of papilledema. Histopathologic evaluation of the optic nerve sheath demonstrated numerous cryptococci. Optic nerve sheath fenestration may be an effective treatment method when high intracranial pressure is contributing to visual loss, even in the presence of involvement of the optic nerve sheath by the fungus.

Keywords: optic nerve sheath, cryptococcal, meningitis, fenestration

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