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Oculogyric crisis in a patient taking metoclopramide

Authors Koban Y, Ekinci M, Cagatay HH, Yazar Z

Received 3 January 2014

Accepted for publication 23 January 2014

Published 19 March 2014 Volume 2014:8 Pages 567—569

DOI https://doi.org/10.2147/OPTH.S60041

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2


Yaran Koban, Metin Ekinci, Halil Huseyin Cagatay, Zeliha Yazar

Department of Ophthalmology, Faculty of Medicine, Kafkas University, Kars, Turkey

Abstract: Oculogyric crisis is an acute dystonic reaction of the ocular muscles characterized by bilateral dystonic elevation of visual gaze lasting from seconds to hours. This reaction is most commonly explained as an adverse reaction to drugs such as antiemetics, antipsychotics, antidepressants, antiepileptics, and antimalarials. Although the incidence of metoclopramide-induced acute dystonic reactions has been reported as 25% in children, there have been few published cases on oculogyric crisis in general. It is important to be able to recognize this ocular side effect because, without a thorough patient history, symptoms can be confused with other diseases such as versive seizures, paroxysmal tonic upward gaze, and encephalopathy. In this paper, we report a case of oculogyric crisis induced by metoclopramide.

Keywords: oculogyric crisis, dystonic reactions, metoclopramide

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