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Obstructive sleep apnea and cardiovascular risk

Authors Punginathn Dorasamy

Published 15 January 2008 Volume 2007:3(6) Pages 1105—1111


Punginathn Dorasamy
Pulmonary Hypertension Clinic, Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada
Abstract: Obstructive sleep apnea (OSA) is a form of sleep disordered breathing characterized by episodes of apnea (during sleep) lasting at least 10 seconds per episode. The apneic periods are associated with arterial hypoxemia and disruption of normal sleep as a result of awakenings. It is increasingly being recognized that OSA is a public health hazard and there is increasing evidence that it is associated with an increase in morbidity (and possibly mortality). Patients with OSA also utilize the healthcare resources at higher rates than control patients long before their diagnosis is confirmed. Early recognition of this condition may lead to earlier treatments (eg, nasal CPAP) with reduction of the risk of cardiovascular diseases such as hypertension, ischemic heart disease, arrhythmias, platelet activation and
pulmonary hypertension.
Keywords: obstructive sleep apnea (OSA), apnea-hypopnea index (AHI), polysomnography, overlap syndrome, C-Reactive protein (CRP), sleep disordered breathing (SDB), Cheynes Stokes respiration-central sleep apnea (CSR-CSA)

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