Novel non-pharmacological insomnia treatment – a pilot study
Authors Pavlova MK, Latreille V, Puri N, Johnsen J, Batool-Anwar S, Javaheri S, Mathew PG
Received 29 December 2018
Accepted for publication 10 June 2019
Published 11 September 2019 Volume 2019:11 Pages 189—195
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Melinda Thomas
Peer reviewer comments 2
Editor who approved publication: Dr Sutapa Mukherjee
Milena K Pavlova,1 Véronique Latreille,1 Nirajan Puri,1 Jami Johnsen,1 Salma Batool-Anwar,2 Sogol Javaheri,2 Paul G Mathew1
1Department of Neurology, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA; 2Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA
Correspondence: Milena K Pavlova
Department of Neurology, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA 02115, USA
Tel +1 617 983 7580
Fax +1 617 983 7582
Objective: The objective of this prospective pilot study was to examine the effects of a novel non-pharmacological device (BioBoosti) on insomnia symptoms in adults.
Methods: Subjects with chronic insomnia were instructed to hold the device in each hand for 8 mins for 6 cycles on a nightly basis for 2 weeks. Outcomes tested included standardized subjective sleep measures assessing sleep quality, insomnia symptoms, and daytime sleepiness. Sleep was objectively quantified using electroencephalogram (EEG) before and after 2 weeks of treatment with BioBoosti, and wrist actigraphy throughout the study.
Results: Twenty adults (mean age: 45.6±17.1 y/o; range 18–74 y/o) were enrolled in the study. No significant side effects were noted by any of the subjects. After 2 weeks of BioBoosti use, subjects reported improved sleep quality (Pittsburgh Sleep Quality Index: 12.6±3.3 versus 8.5±3.7, p=0.001) and reduced insomnia symptoms (Insomnia Severity Index: 18.2±5.2 versus 12.8±7.0, p<0.001). Sleepiness, as assessed by a visual analog scale, was significantly reduced after treatment (5.7±2.8 versus 4.0±3.3, p=0.03).
Conclusion: BioBoosti use yielded an improvement in insomnia symptoms. Larger placebo-controlled studies are needed to fully assess efficacy.
Keywords: insomnia, non-pharmacological treatment, sleep quality, actigraphy, electroencephalography
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