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Novel interfaces for light directed neuronal stimulation: advances and challenges

Authors Bareket-Keren L, Hanein Y

Received 8 July 2013

Accepted for publication 21 August 2013

Published 6 May 2014 Volume 2014:9(Supplement 1) Pages 65—83


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Lilach Bareket-Keren,1,2 Yael Hanein1,2

School of Electrical Engineering, Tel-Aviv University, 2Tel-Aviv University Center for Nanoscience and Nanotechnology, Tel-Aviv University, Tel-Aviv, Israel

Abstract: Light activation of neurons is a growing field with applications ranging from basic investigation of neuronal systems to the development of new therapeutic methods such as artificial retina. Many recent studies currently explore novel methods for optical stimulation with temporal and spatial precision. Novel materials in particular provide an opportunity to enhance contemporary approaches. Here we review recent advances towards light directed interfaces for neuronal stimulation, focusing on state-of-the-art nanoengineered devices. In particular, we highlight challenges and prospects towards improved retinal prostheses.

Keywords: neuronal stimulation, light, retinal implant, prosthesis, quantum dots, conducting polymers, photoconductive

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