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Neuropsychological profile in a specific cohort of HIV patients infected postnatally: a cross-sectional study

Authors Riva S, Cutica I, Pravettoni G

Received 17 March 2015

Accepted for publication 19 August 2015

Published 9 October 2015 Volume 2015:6 Pages 1—6

DOI https://doi.org/10.2147/NBHIV.S84838

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Stephen Ferrando

Silvia Riva,1,2 Ilaria Cutica,1 Gabriella Pravettoni1,3

1Department of Health Sciences, University of Milan, 2Department of Neuroscience, IRCCS, Istituto di Ricerche Farmacologiche "Mario Negri", 3European Institute of Oncology, Milan, Italy

Abstract: HIV-associated neurocognitive disorders (HANDs) are one of the most important complications of HIV infection reported in the current literature. Although HANDs have been closely studied in vertically infected HIV populations or in specific subgroups such as drug abusers or homosexuals, they have been completely understudied in hemophilia patients with HIV, infected through transfusions postnatally. For this reason, it seemed interesting to evaluate the presence of HAND in this specific population. The aim of this work is to present a study protocol aimed at assessing the neuropsychological profile of HIV+ hemophilia patients compared with that of HIV– hemophilia patients. This is the first European study to evaluate the neuropsychological profile of HIV+ adult hemophiliacs prospectively.

Keywords: neuropsychological profile, neuropsychology, HIV, cognitive disorders, hemophilia

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