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Neonatal necrotizing enterocolitis

Authors Maheshwari A, Corbin, Schelonka R

Published 24 August 2011 Volume 2011:1 Pages 39—53

DOI https://doi.org/10.2147/RRN.S23459

Review by Single anonymous peer review

Peer reviewer comments 3


Akhil Maheshwari1, Laura L Corbin2, Robert L Schelonka2
1Division of Neonatology and Center for Neonatal and Pediatric Gastrointestinal Disease, Department of Pediatrics, University of Illinois at Chicago, IL, 2Division of Neonatology, Department of Pediatrics, Oregon Health and Sciences University, Portland, OR, USA

Abstract: Necrotizing enterocolitis is the most common gastrointestinal emergency in preterm neonates and a major cause of morbidity and mortality in premature infants born before 32 weeks of gestation or with a birth weight less than 1500 g. In this review, we discuss predisposing factors, clinical manifestations, and the quality of evidence for various preventive and therapeutic strategies.

Keywords: necrotizing enterocolitis, inflammation, mucosa, pneumatosis, neonate

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