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Necrosis of the thumb after inadvertent injection of diclofenac in the radial artery: a case report

Authors Shon HC, Park JK, Kang SW, Yang JY

Received 29 August 2017

Accepted for publication 9 November 2017

Published 13 December 2017 Volume 2017:10 Pages 2803—2806

DOI https://doi.org/10.2147/JPR.S150306

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Minal Joshi

Peer reviewer comments 2

Editor who approved publication: Dr E Alfonso Romero-Sandoval


Hyun-Chul Shon, Ji-Kang Park, Sang-Woo Kang, Jae-Young Yang

Department of Orthopaedic Surgery, College of Medicine, Chungbuk National University, Cheongju, Korea

Abstract: Inadvertent intra-arterial drug injection occurs rarely, but it can cause very serious clinical complications, and thus, awareness of inadvertent intra-arterial drug injection is needed. The complications mainly result from iatrogenic reasons and can occur because of vascular variations in the arteries, under circumstances where normal intravenous injection is difficult, or in drug abusers who perform self-injection. The adverse effect associated with intra-arterial drug injection is serious and may lead to necrosis, requiring amputation of the affected extremity, infection, pseudoaneurysm, rhabdomyolysis, compartment syndrome, and permanent disability. However, the etiology of such adverse effects has not been clearly identified and treatment methods have not yet been established. We encountered a patient who developed necrosis of the thumb after an inadvertent injection of diclofenac sodium in the radial artery due to variations in the forearm arteries. Here, we report the prevention and treatment of, and precautions against, the dangers of intra-arterial drug injection.

Keywords: intra-arterial drug injection, diclofenac sodium, thumb necrosis

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