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Cost and clinical consequences of smoking cessation in outpatients after cardiovascular disease: a retrospective cohort study

Authors Sicras-Mainar A, Díaz-Cerezo S, Sanz de Burgoa V, Navarro-Artieda R

Received 26 January 2013

Accepted for publication 5 April 2013

Published 19 August 2013 Volume 2013:5 Pages 419—427


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 4

Antoni Sicras-Mainar,1 Silvia Díaz-Cerezo,2 Verónica Sanz de Burgoa,3 Ruth Navarro-Artieda4

1Directorate of Planning, Badalona Serveis Assistencials SA, Badalona, Spain; 2Health Economics and Outcomes Research Department, Pfizer, SLU, Alcobendas, Spain; 3Medical Department, Pfizer, SLU, Alcobendas, Spain; 4Medical Documentation Unit, Hospital Germans Trias i Pujol, Badalona, Spain

Abstract: This cohort retrospective study explored the cost and clinical consequences of smoking cessation in outpatients after cardiovascular events (CVEs), in Spain. A total of 2,540 patients (68.1 years; 60.7% male; 8.4% smokers, 52.9% ex-smokers, and 38.7% never smokers) fulfilling the selection criteria and followed up throughout a period of 36 months after the event were considered eligible for analysis. Total costs were higher among current smokers in comparison with ex-smokers and never smokers (€7,981 versus [vs] €7,322 and €5,619, respectively) (P < 0.001). Both health care costs (€6,273 vs €5,673 and €4,823, respectively) (P < 0.001) and loss of productivity at work costs (€1,708 vs €1,650 and €796, respectively) (P < 0.001) accounted for such differences. There was also a difference in CVE recurrence rates (18.6% vs 16.5% and 9.6%, respectively) (P < 0.01). Smoking cessation in CVE outpatients was associated with lower cost and risk of CVE recurrence compared with smokers, and their health status was similar to that of never smokers, in routine clinical practice in Spain.

Keywords: mortality, health resources, health care costs

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