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Nanoantibiotics: strategic assets in the fight against drug- resistant superbugs

Authors Khurana C, Chudasama B

Received 14 October 2016

Accepted for publication 30 October 2016

Published 15 March 2018 Volume 2018:13(T-NANO 2014 Abstracts) Pages 3—6


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Lei Yang

Chandni Khurana, Bhupendra Chudasama

Laboratory of Nanomedicine, School of Physics and Materials Science, Thapar University, Patiala, Punjab, India

Abstract: Antimicrobial characteristics of metals reveal that Ag despite its economic constraints remains the most popular antibiotic agent. Antimicrobial characteristics of copper nanoparticles (CNPs) are not well understood. To our knowledge, no systematic comparative study on microbial properties of silver nanoparticles (SNPs) and CNPs exists. In this article, a comparative study on microbial properties of engineered metal nanoantibiotics against clinically important strains has been attempted. Our results indicate that biocidal activities of CNPs are better than SNPs. Minimum inhibitory concentration (MIC) values of CNPs are 10 times lower than the corresponding MICs of SNPs. These improved biocidal activities of CNPs would make it affordable and potent nontraditional antibiotics against which microbes are least susceptible to develop any drug resistance.

Keywords: antibiotics, silver, copper, nanoparticles

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