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MUC1 positive cutaneous metastasis with transepidermal elimination from a breast carcinoma

Authors Luna A, Merino ME, Alberdi CG, Abba MC, Segal-Eiras A, Croce MV

Received 7 August 2013

Accepted for publication 6 September 2013

Published 7 November 2013 Volume 2013:6 Pages 81—84

DOI https://doi.org/10.2147/IMCRJ.S52614

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 5


Amalia Luna, Maria Emilia Merino, Cecilio G Alberdi, Martin C Abba, Amada Segal-Eiras, Maria Virginia Croce

Center of Basic and Applied Immunological Research, Faculty of Medical Sciences, National University of La Plata, Argentina

Abstract: Breast cancer is the most common cause of cutaneous metastases from internal malignancies. Generally, the neoplastic cells are located in the dermis or hypodermis, while a finding of transepidermal elimination on cutaneous metastases is exceptional. In this report we present a patient with perforating cutaneous metastases from breast cancer with mucin 1 expression. Cutaneous, bone, lung, and hepatic lesions were detected two years after the diagnosis of the primary tumor.

Keywords: breast cancer, cutaneous metastasis, transepidermal elimination, MUC1

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