Back to Journals » Clinical Interventions in Aging » Volume 7

Modified supracricoid laryngectomy: oncological and functional outcomes in the elderly

Authors Allegra E, Franco T, Trapasso S, Domanico R, La Boria A, Garozzo

Received 22 September 2012

Accepted for publication 13 October 2012

Published 8 November 2012 Volume 2012:7 Pages 475—480

DOI https://doi.org/10.2147/CIA.S38410

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Eugenia Allegra, Teresa Franco, Serena Trapasso, Rossana Domanico, Alessandro La Boria, Aldo Garozzo

Department of Otolaryngology- Head and Neck Surgery, University of Catanzaro, Catanzaro, Italy

Background: Supracricoid laryngectomy is an organ preservation surgical technique for early-stage glottic tumors. Modified supracricoid laryngectomy using sternohyoid muscles for neoglottis reconstruction is a new surgical technique. This report evaluates oncological and functional outcomes of this new technique and its feasibility in elderly patients.
Methods: Clinical records from 21 consecutive patients affected by glottic cancer and treated by modified SCL between 2004 and 2009 were retrospectively reviewed. Postoperative parameters and quality of voice after modified SCL were retrospectively reviewed. Actuarial overall survival, disease-specific survival rates, and recurrence-free survival rates were assessed. The functional and oncological outcomes of patients over 65 years were compared with those of patients younger than 65 years of age.
Results: There were no postoperative complications and all of the patients had complete swallowing rehabilitation. Twenty of the 21 patients had decannulation. Two patients received total laryngectomy for locoregional relapse. Overall survival and disease-specific survival rates were 100%. Recurrence-free survival rates were 90.1% and 90% in patients younger and older than 65 years of age, respectively. The larynx preservation index was lower in patients who were older than 65 years of age. The postoperative courses with regard to functional outcome and voice quality in elderly patients were similar to those of patients younger than 65 years of age.
Conclusion: Modified SCL is a new open organ preservation surgical technique that is oncologically safe. The positive functional and oncological outcomes of this surgical procedure allow it to be performed in elderly patients.

Keywords: supracricoid laryngectomy, modified, early glottic cancer, cricohyoidoepiglottopexy, cricohyoidopexy, elderly, larynx, cancer

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Other articles by this author:

Use of PET/CT to detect local and regional laryngeal cancer recurrence after surgery

Allegra E, Saita V, De Natale M, Marino N, Trapasso S, Tamburrini S, Alessio C, Ippolito M

Reports in Medical Imaging 2017, 10:31-36

Published Date: 15 June 2017

Ectopic lingual thyroid with vascular anomalies

Bianco MR, La Boria A, Franco T, Ferrise P, Allegra E

International Medical Case Reports Journal 2013, 6:55-58

Published Date: 4 September 2013

Cancer stem cells in head and neck cancer

Allegra E, Trapasso S

OncoTargets and Therapy 2012, 5:375-383

Published Date: 21 November 2012

Role of CD44 as a marker of cancer stem cells in head and neck cancer

Trapasso S, Allegra E

Biologics: Targets and Therapy 2012, 6:379-383

Published Date: 1 November 2012

Quality of life in patients treated by organ preservation surgery for early laryngeal carcinoma

Allegra E, Franco T, Trapasso S, Aragona T, Domanico R, Garozzo A

Open Access Surgery 2012, 5:27-32

Published Date: 15 October 2012

Readers of this article also read:

Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles

Prozorova GF, Pozdnyakov AS, Kuznetsova NP, Korzhova SA, Emel’yanov AI, Ermakova TG, Fadeeva TV, Sosedova LM

International Journal of Nanomedicine 2014, 9:1883-1889

Published Date: 16 April 2014

Methacrylic-based nanogels for the pH-sensitive delivery of 5-Fluorouracil in the colon

Ashwanikumar N, Kumar NA, Nair SA, Kumar GS

International Journal of Nanomedicine 2012, 7:5769-5779

Published Date: 15 November 2012

A novel preparation method for silicone oil nanoemulsions and its application for coating hair with silicone

Hu Z, Liao M, Chen Y, Cai Y, Meng L, Liu Y, Lv N, Liu Z, Yuan W

International Journal of Nanomedicine 2012, 7:5719-5724

Published Date: 12 November 2012

Cross-linked acrylic hydrogel for the controlled delivery of hydrophobic drugs in cancer therapy

Deepa G, Thulasidasan AK, Anto RJ, Pillai JJ, Kumar GS

International Journal of Nanomedicine 2012, 7:4077-4088

Published Date: 27 July 2012

Crystallization after intravitreal ganciclovir injection

Pitipol Choopong, Nattaporn Tesavibul, Nattawut Rodanant

Clinical Ophthalmology 2010, 4:709-711

Published Date: 14 July 2010