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Megestrol acetate in cachexia and anorexia

Authors Shing-Shing Yeh, Michael W Schuster

Published 15 January 2007 Volume 2006:1(4) Pages 411—416

Shing-Shing Yeh1, Michael W Schuster2

1Northport vAMC, Geriatric division, Northport, NY 11768; 2Weill Medical College of Cornell University and the New York Presbyterian Hospital, New York, NY 10021, USA

Abstract: The aim is to review major clinical trials that have used megestrol acetate (MA) in the treatment of cachexia across several disease states. A review of general usage and potential side-effects are discussed. A theory that the newly approved nanocrystal formation of MA can better deliver this potent medication for treatment will also be reviewed.

Keywords: megestrol acetate, nanocrystalline particles, cachexia

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