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Mechanisms Underlying Therapeutic Effects Of Traditional Chinese Medicine On Gastric Cancer

Authors Yang L, Zhao L, Zeng T, Chen H, Shao J, Yang S, Tao Z, Yang J, Chen T, Lin X, Chen X, Tang M

Received 4 June 2019

Accepted for publication 27 August 2019

Published 16 September 2019 Volume 2019:11 Pages 8407—8418

DOI https://doi.org/10.2147/CMAR.S218214

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Amy Norman

Peer reviewer comments 2

Editor who approved publication: Dr Seema Singh


Linjun Yang,1,* Liqian Zhao,1,* Tianni Zeng,1 Hong Chen,1 Jingjing Shao,1 Song Yang,1 Zheying Tao,1 Jingqin Yang,1 Tongke Chen,1 Xiaokun Lin,2 Xiwen Chen,1 Mosheng Tang3

1Department of Laboratory Animal Centre, Laboratory Animal Centre, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2Department of Pediatric Surgery, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Radiotherapy and Chemotherapy, Lishui City People’s Hospital, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Mosheng Tang
Department of Radiotherapy and Chemotherapy, Lishui City People’s Hospital, The Sixth Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, People’s Republic of China
Tel +86 0577 86689908
Email tangmosheng@yeah.net
Xiwen Chen
Laboratory Animal Centre, Wenzhou Medical University, Lucheng district, Wenzhou, Zhejiang, People’s Republic of China
Tel +86 0577 86689907
Email chenxiwen7115@163.com

Abstract: Gastric cancer (GC) is one of the most common malignant tumors in the world. It is the fourth most common cancer and has the second highest mortality rate globally. Metastasis is an important feature of gastric cancer and is the most common cause of death. Exploring the mechanism underlying the metastasis of gastric cancer and searching for new drug targets has become the focus of several studies. Traditional Chinese medicine may show promise for treatment of gastric cancer. In this review, we report the recent progress in research on the anti-metastasis activity of Chinese medicine, to facilitate clinical development of treatments for gastric cancer.

Keywords: Chinese medicine, metastasis, gastric cancer, cell cycle, angiogenesis

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