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Mayer-Rokitansky-Kuster-Hauser syndrome: a review

Authors Londra L, Chuong F, Kolp L

Received 15 June 2015

Accepted for publication 30 July 2015

Published 2 November 2015 Volume 2015:7 Pages 865—870

DOI https://doi.org/10.2147/IJWH.S75637

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Fredrick Rosario Joseph

Peer reviewer comments 2

Editor who approved publication: Professor Elie Al-Chaer


Laura Londra, Farah S Chuong, Lisa Kolp

Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University, Baltimore, MD, USA

Abstract: The congenital aplasia or severe hypoplasia of mullerian structures is infrequent. However, the features of normal female endocrine function paired with the absence of a functional uterus and vagina makes it a fascinating entity. The diagnosis and work-up in these patients has become very efficient, thanks to the use of imaging, and there are multiple successful procedures for the creation of a neovagina. In recent years, infertility treatment options through in vitro fertilization have also become available as part of the long-term care of these patients.

Keywords: vaginal agenesis, neovagina, MRKH, mullerian agenesis

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