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Managing nut-induced anaphylaxis: challenges and solutions

Authors Lomas J, Järvinen K

Received 23 May 2015

Accepted for publication 19 August 2015

Published 29 October 2015 Volume 2015:8 Pages 115—123


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 7

Editor who approved publication: Dr Amrita Dosanjh

Jeanne M Lomas, Kirsi M Järvinen

Division of Pediatric Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA

Abstract: The prevalence of peanut and tree nut allergy in the USA has increased, especially in the pediatric population. Nut allergy remains the leading cause of fatal anaphylactic reactions. Management of anaphylaxis includes not only treatment of symptoms during a reaction, but strict dietary avoidance and education on potential situations, which may place the patient at high risk for accidental exposure. Cross-reactivity between various nuts along with various cross-contamination sources should be discussed with all nut-allergic individuals. Exciting research continues to emerge on other potential treatments for patients allergic to nuts, including allergen immunotherapy. Results of such interventions have been encouraging, though further studies are needed regarding safety and long-term outcomes before these can be applied to clinical practice.

Keywords: peanut, tree nut, anaphylaxis, cross-reactivity, avoidance, immunotherapy

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