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Management Strategies of Melkersson-Rosenthal Syndrome: A Review

Authors Dhawan SR, Saini AG, Singhi PD

Received 29 August 2019

Accepted for publication 22 January 2020

Published 26 February 2020 Volume 2020:13 Pages 61—65

DOI https://doi.org/10.2147/IJGM.S186315

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Sumeet R Dhawan,1 Arushi G Saini,2 Pratibha D Singhi2,3

1Department of Pediatrics, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, 133207, India; 2Pediatric Neurology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India; 3Medanta, The Medicity, Gurgaon, Haryana, India

Correspondence: Pratibha D Singhi Medanta, The Medicity, Gurgaon, Haryana, India
Tel +91 8168186894
Email doctorpratibhasinghi@gmail.com

Abstract: Melkerrson-Rosenthal syndrome is a rare disorder of unknown aetiology and characterized by the triad of oro-facial edema, facial nerve palsy, and furrowing of the tongue. Two or more of the above are essential for making a clinical diagnosis. The mainstay of treatment is corticosteroids. Intralesional triamcinolone acetonide may be used for the treatment of oro-facial edema. Another treatment option for oro-facial edema includes intralesional betamethasone, along with oral doxycycline. The review discusses the management strategies in Melkersson-Rosenthal syndrome.

Keywords: facial palsy, Bell’s palsy, facial edema, lip edema, orofacial granulomatosis, recurrent facial palsy, fissured tongue, lingua plicata


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