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Management of pediatric corneal limbal dermoids

Authors Pirouzian A

Received 28 November 2012

Accepted for publication 15 January 2013

Published 28 March 2013 Volume 2013:7 Pages 607—614


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Amir Pirouzian1,2

1Tayani Institute, Division of Ophthalmology and Cornea, Mission Viejo in affiliation with Children’s Hospital of Orange County at Mission Hospital, CA, USA; 2Rady’s Children’s Hospital of San Diego, San Diego, CA, USA

Abstract: This paper reviews the data in the published literature (PubMed from 1937 to 2011) concerning the medical and surgical management of pediatric limbal dermoids. Current standard medical treatment for grade I pediatric limbal dermoids (ie, with superficial corneal involvment) is initially conservative. In stages II (ie, affecting the full thickness of the cornea with/without endothelial involvement) and III (ie, involvement of entire cornea and anterior chamber), a combination of excision, lamellar keratoplasty, and amniotic membrane and limbal stem cell tranplantation are advocated. Combinations of these approaches seem to yield better and more stable long-term ocular surface cosmesis and fewer complications in comparison with traditional methods of excision and lamellar keratoplasty. Management of amblyopia (i.e. occlusion treatment, chemical penalization with/without spectacle wear, etc) must continue after surgical excision to yield optimal results when or if the surgery is done at a younger age.

Keywords: limbal dermoid, amniotic membrane, surgical management, tissue adhesive

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