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Malignant Arrhythmias as the Unmasked Manifestation of Thyroid Storm

Authors Shang W, Ma QB

Received 3 June 2020

Accepted for publication 5 August 2020

Published 24 September 2020 Volume 2020:13 Pages 693—698

DOI https://doi.org/10.2147/IJGM.S265833

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Wen Shang, Qing-Bian Ma

Department of Emergency, Perking University Third Hospital, Beijing 100191, People’s Republic of China

Correspondence: Qing-Bian Ma
Department of Emergency, Perking University Third Hospital, 49 Huayuan North Road, Beijing 100191, People’s Republic of China
Tel +86-10-82264047
Fax +86-10-82264040
Email maqingbian@medmail.com.cn

Abstract: Thyroid storm is usually due to a severe exacerbation of a preexisting thyrotoxicosis, which later leads to decompensation in different organ systems. Thyroid storm with malignant arrhythmia is rare, but the mortality rate is high. Malignant arrhythmia has usually occurred in some patients with hypokalemia or ischemic heart disease. The presentation of these arrhythmias in the initial phase of the disease is much less common, and only a few isolated cases are described in the scientific literature. This paper analyzes and summarizes the clinical characteristics of this disease through literature reviews, for clinicians early detection and diagnosis of this disease. We report a 51-year-old woman with diarrhoea, fever, thyroid storm, ventricular fibrillation and no potential heart disease. The case report is discussed using relevant data from literature. A total of 9 patients were reported in the literature, totalling 10 cases with ours, including 7 cases of ventricular fibrillation and 3 cases of ventricular tachycardia. Most of the treatments were antithyroid drugs, hormones and beta-receptor blockers, and 3 death cases. Patients with thyroid crisis need to be closely monitored for malignant arrhythmias. Early diagnosis and treatment may save lives.

Keywords: thyroid storm, malignant arrhythmia, ventricular tachycardia

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