Making a choice: initial fraction of inspired oxygen for resuscitation at birth of a premature infant less than 32 weeks gestational age
Gregory P Moore,1–3 Behdad Navabi2
1Department of Pediatrics, Division of Neonatology, Children's Hospital of Eastern Ontario, 2Department of Obstetrics and Gynecology, Division of Newborn Care, The Ottawa Hospital General Campus, 3Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada
As briefly noted by Abdel-Hady and Nasef in their 2012 publication in Research and Reports in Neonatology,1 the best initial fraction of inspired oxygen (FiO2) to use during resuscitation of preterm neonates <32 weeks gestational age (GA) has not been clearly elucidated. Most recent neonatal resuscitation guidelines leave the difficult choice of the actual FiO2 in the hands of individual physicians. We believe that this letter, through review and discussion of the recent published literature, will aid physicians in this choice and confirm that, as per the opinion of Abdel-Hady and Nasef, the best present evidence-based choice for the initial FiO2 for resuscitating preterm infants <32 weeks GA appears to be 30%. However, determination of the ideal initial resuscitation gas requires further research assessing both short-term and long-term outcomes.
View original paper by Abdel-Hady and Nasef.
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