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Long-Term Azithromycin Maintenance Treatment in Patients with Frequent Exacerbations of Chronic Obstructive Pulmonary Disease

Authors Talman S, Uzun S, Djamin RS, Baart SJ, Grootenboers MJJH, Aerts J, van der Eerden M

Received 7 October 2020

Accepted for publication 7 January 2021

Published 1 March 2021 Volume 2021:16 Pages 495—498

DOI https://doi.org/10.2147/COPD.S284397

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Richard Russell


Sander Talman,1 Sevim Uzun,2 Remco S Djamin,1 Sara J Baart,3 Marco JJH Grootenboers,1 Joachim Aerts,2 Menno van der Eerden2

1Amphia Hospital Breda, Department of Pulmonary Medicine, Breda, 4800RK, the Netherlands; 2Erasmus Medical Centre Rotterdam, Department of Pulmonary Medicine, Rotterdam, 3015 CE, the Netherlands; 3Erasmuc Medical Centre Rotterdam, Department of Biostatistics, Rotterdam, 3015 CE, the Netherlands

Correspondence: Sander Talman Tel +31 76 595 5351
Email [email protected]

Abstract: Macrolides are effective in reducing the number of exacerbations in COPD patients with the frequent exacerbator phenotype. Our study did not show a persistent effect of azithromycin on exacerbation frequencies after more than one year of usage.

Keywords: Macrolide, long-term, exacerbations, COPD, COLUMBUS

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