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RETRACTED ARTICLE: LncRNA EMX2OS Induces Proliferation, Invasion and Sphere Formation of Ovarian Cancer Cells via Regulating the miR-654-3p/AKT3/PD-L1 Axis

Authors Duan M, Fang M, Wang C, Wang H, Li M

Received 28 August 2019

Accepted for publication 9 February 2020

Published 24 March 2020 Volume 2020:12 Pages 2141—2154

DOI https://doi.org/10.2147/CMAR.S229013

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Professor Harikrishna Nakshatri



This paper has been retracted.

Duan M, Fang M, Wang C, Wang H, Li M. Cancer Manag Res. 2020;12:2141–2154.

We, the Editors and Publisher of Cancer Management and Research, have retracted the following article.

Following publication of the article, concerns were raised about the duplication of images from Figures 2, 3 and 4 with images from other unrelated articles. Specifically,

  • Images for Figure 2C have been duplicated with images for Figure 2D from Xu B, Gong X, Zi L, et al. Silencing of DLEU2 suppresses pancreatic cancer cell proliferation and invasion by upregulating microRNA-455. Cancer Sci. 2019;110:1676–1685. https://doi.org/10.1111/cas.13987 and Figure 2d from Cui K, Jin S, Du Y, et al. Long noncoding RNA DIO3OS interacts with miR-122 to promote proliferation and invasion of pancreatic cancer cells through upregulating ALDOA. Cancer Cell Int. 2019;19:202. https://doi.org/10.1186/s12935-019-0922-y.
  • An image for Figure 3B has been duplicated with an image for Figure 4B from Wang X, Meng R, Hu QM. LINC00319-Mediated miR-3127 Repression Enhances Bladder Cancer Progression Through Upregulation of RAP2A. Front. Genet. 2020;11:180. https://doi.org/10.3389/fgene.2020.00180.
  • Images for Figure 4F have been duplicated with images for Figure 2D from Xu B, et al (2019) and Figure 2d from Cui K, et al (2019).
  • The image for Figure 2C, EMX2OS vector(-) has been duplicated with the image for Figure 4G, EMX2OS vector(+) miR-654 mimic(+).
  • The image for Figure 3C, ES-2, EMX2OS siRNA-2 has been duplicated with the image for Figure 3D, SKOV-3, Control vector.
  • The image for Figure 4G, EMX2OS vector(-) miR-654 mimic(-) has been duplicated with the image for Figure 4G, EMX2OS vector(+) miR-654 mimic(+).

The authors did not respond to our queries and were unable to provide an explanation for the duplicated images or provide data for the study. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article and the authors were notified of this.

We have been informed in our decision-making by our editorial policies and COPE guidelines.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.

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